Sickle cell disease is an inherited condition that is most common among people whose ancestors come from Africa, the Middle East, the Mediterranean basin, and India.
If both mother and father carry the trait for a sickle cell disorder, there is a:
- 25% chance with each pregnancy for that child to have sickle cell disease.
- 50% chance for the child to have a trait
- 25% chance that the child will not have disease or trait.